1Peter's Spidey Sense
When Doctor Strange smacks Peter’s astral form out of his body in Spider-Man: No Way Home, you can see that Peter’s head has transparent versions of the classic wavy Spider-Sense lines.
During the final sequence in Spider-Man: No Way Home, when multiple ripples in the fabric of reality open, several other classic enemies of Spider-Man can be seen, waiting to enter the MCU dimension. Among them, you can recognize Rhino, who's the only major villain from previous movies along with Harry Osborn not to come back, and Kraven the Hunter.
3Spider-Men Pointing Meme
The image of two Spider-Men pointing at each other is a popular internet meme. The image is taken from the 60's Spider-Man cartoon episode in which two people in Spider-Man costumes are pointing at each other. There is also a variation of the meme with three Spider-Men pointing at each other. Though it is not obvious, this meme is referenced in Spider-Man: No Way Home when the three Peter Parkers are pointing at each other in the lab (albeit without the costume) when Ned calls out for Peter.
Willem Dafoe only agreed to reprise his role as the Green Goblin in Spider-Man: No Way Home on the condition that he still be allowed to perform the majority of his own stunts as he did in Spider-Man (2002).
5No Way Home-Hawkeye Easter Egg
In Spider-Man: No Way Home, MJ is mobbed by the Big Apple’s curious public, and Spider-Man swings in to save the day. As the pair hurtle through the skyscrapers, we catch a glimpse of a Hawkeye (2021) Easter egg: a digital billboard for Rogers: The Musical. The first episode of Hawkeye (2021) sees Clint Barton head to Broadway to watch a musical recreation of the events of the first Avengers movie, aptly titled Rogers: The Musical.
6Liz Toomes Cameo
In Spider-Man: No Way Home, just before Dr. Strange chases Peter Parker into the Mirror Dimension, he runs past a newsstand selling copies of People magazine. The current issue features an exclusive interview with Liz Toomes regarding Peter’s outing and calling him a liar.
7Ned Leeds as Hobgoblin
MCU Spider-Man fans have speculated as to whether Jacob Batalon’s portrayal of Ned Leeds will take up the Hobgoblin mantle in future MCU movies as he does in the original comics. This is either foreshadowed or referenced in Spider-Man: No Way Home when Tobey's Spider-Man mentions that his best friend died trying to kill him. Ned then promises his Peter that he won’t do the same.
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8Willem Dafoe's Teeth
Like in the original Spider-Man movie, Willem Dafoe once again for Spider-Man: No Way Home wore prosthetic teeth as Norman Osborne and his real teeth were shown for the Green Goblin persona. It's subtle and easy to miss, but a great detail.
9Peter's Cut Tie
In Spider-Man: No Way Home when Peter’s tie is cut in half while fighting doc ock, he’s seen dressed the same way as Tobey in spider man 3 when he was on his way to propose to MJ, and Harry blindsided him. During the fight, Tobey's tie rips in half too.
10Goblin Abandoning Suit
In Spider-Man: No Way Home, there is a shot of Norman running away while his Goblin mask is lying shattered next to a dumpster, mirroring the shot of Peter Parker tossing his Spider-Man suit in a trash can from Spider-Man 2.