1Do the Bartman
The Simpsons released an album in 1990 and the lead single "Do the Bartman" was a worldwide hit. It was co-produced by Michael Jackson, who also provided background vocals and was a huge fan of the show. Following his death, FOX played the video before an episode as a tribute to Michael.
2. In two episodes of the first season of The Simpsons, Lou the cop was colored yellow. It wasn’t till Season 2 that they kept him black.
3. Milhouse Van Houten is allergic to honey, wheat, dairy, non-dairy, mistletoe, holly, the red part of candy canes, and to his own tears.
4. The Simpsons episode “22 Short Films About Springfield” was a backdoor pilot for a proposed series. 'Tales from Springfield' would have told three different short stories per week, focusing on secondary characters and telling stories about the Simpsons family members’ past or future.
5. Mr. Burns' telephone greeting in The Simpsons, 'Ah-Hoy!' was actually how Alexander Graham Bell thought people should answer the telephone when he invented it.
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6Nuclear physics
Simpsons characters Lenny Leonard and Carl Carlson both possess master's degrees in nuclear physics.
7. Homer Simpson’s conversations with his own brain were often introduced because it filled time and was easy for animators to work on. Homer's conversations with his brain were used several times during the 4th season, but were later phased out after producers “used every possible permutation.”
8. On The Simpsons episode where Bart, Nelson, Milhouse and Ralph become a boy band, Justin Timberlake was reluctant to say “Word” since he swore it was something he would never say, so as a joke the editing team reused the one take where he said “Word” after nearly every line.
9. If you disregard the floating timeline in The Simpsons, Mr. Burns is 128 years old (as of 2020) being born in 1892.
10. The Simpsons' "Bart prank calls Moe's Tavern" is a reference to two guys who used to prank call a bar in Jersey City and became famous for the recordings.
11Lisa Simpson
Lisa Simpson remains a vegetarian as a promise from the show's staff to Paul McCartney.
12. Bart Simpson's first name was chosen because it was an anagram of the word 'Brat'. His full name is Bartholomew Jojo Simpson.
13. The Simpsons' Ned Flanders was a real hell-raiser as a kid. Befuddled, his parents put young Ned in a University of Minnesota treatment which involved eight months of continuous spanking. The treatment worked so well that it rendered Flanders unable to express any anger at all.
14. The Simpsons episode where Bart gets an elephant was based on a real Price is Right incident in 1956.
15. Mayor Quimby's full name in ‘The Simpsons’ is Joseph Fitzgerald O'Malley Fitzpatrick O'Donnell The Edge "Joe" Quimby.
16Milhouse Van Houten
Milhouse Van Houten from The Simpsons was named after Richard Milhous Nixon because it was the most "unfortunate name Matt Groening could think of for a kid."
17. The Comic Book Guy from The Simpsons has a real name, Jeffrey Albertson.
18. Apu Nahasapeemapetilon from The Simpsons has a doctorate in computer science.
19. The middle name of Nelson Muntz from The Simpsons is ‘Mandela.’
20. The word 'Jebus' as used in the Simpsons is in fact an old name for Jerusalem, named after the tribe who had built it.
21We want Chilli Willi
In The Simpsons when Barney shouts "We want Chilli Willi" to the Red Hot Chili Peppers, he is actually calling for "Chilli Willi and the Red Hot Peppers," who were a real pub-rock band from the early 1970s.
22. The Simpsons was nearly cancelled before its first episode. When the first episode came back, the animation was so appalling that the staff considered halting show production. 70% of the animation had to be redone before it could air.
23. The Simpsons was originally supposed to end in December 2011 with the series finale episode that eventually aired called "Holidays of Future Passed."
24. The aliens from The Simpsons, Kang and Kodos, have a surname: Johnson.
25. The made-up word from a 1996 Simpsons episode "embiggen" was officially added to the Merriam Webster Dictionary in early March of 2018.