Jo Cameron's Pain-Free Mutation

Jo Cameron, a retired teacher from the Scottish Highlands, has congenital insensitivity to pain-believed to stem from rare mutations in the FAAH and FAAH OUT genes-which causes elevated levels of endocannabinoids like anandamide, reducing her ability to feel both pain and anxiety. Despite numerous surgeries, burns, fractures, and even childbirth throughout her life, she has never required painkillers.

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