Tycho Brahe

Danish astronomer, alchemist, and nobleman Tycho Brahe lost his nose after challenging another scientist to a duel to settle once and for all whose mathematical formula was better. He wore a metal prosthetic nose for the rest of his life. He also had a pet moose that died when it drank too much beer and fell down a flight of stairs. In 1601, Tycho attended a party during which he held himself from going to the bathroom, subsequently suffered a burst bladder, and died 10 days later.