Avengers Assemble

In Avengers Assemble (2012), Captain America tells Iron Man, "You're not the guy to make the sacrifice play," and Iron Man tells Captain America, "Everything special about you came out of a bottle." In Avengers: Endgame, each proves the other wrong. Iron Man sacrifices himself to defeat Thanos, while Captain America proves himself worthy by being able to wield Thor's hammer, Mjolnir.